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     One of the most valuable components
of indigenous medical systems for over 40 centuries, has been the Mangifera indica
leaves, the largest fruit-bearing tree ever discovered in India. The
usage of Mangifera indica leaves as a
medicinal agent dates back to as early as
327 BCE. The existence of some major
groups of phytochemical constituents such as saponins, anthraquinones, terpenoids,
etc. and therapeutically active components such as mangiferin, stigmasterol, friedelin, lupeol, etc. have also been reported from Mangifera indica
leaves.

 

     There
is a scarcity of scientific information in support of their success, whilst the
leaves have been traditionally used as an antibacterial
and immunomodulatory agent. Mangifera indica leaves are also used as an
antibacterial agent in Nigerian folk herbalism.
To ascertain whether or not there is a scientific basis for this use, the effect of the blood glucose level was evaluated in normoglycaemic,
glucose-induced hyperglycaemic and streptozotocin
(STZ) induced diabetic rodents such as Rattus (rat). The aqueous extract
given orally did not modify the blood glucose levels in either normoglycaemic
or STZ-induced (streptozotocin) diabetic rodents specifically Rattus (rat).

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Aqueous extracts of Mangifera indica leaves showed remarkable influence on reproductive functions,
wound regeneration and antidiabetic tasks. Alcoholic extracts of Mangifera
indica leaves have been found containing TNF- (Tumor necrosis factor), ILIB
expression and B-lactamase producing enteric
bacterial development.

 

     Mangifera indica leaves are equipped with
a broad outer cuticle to avoid the loss of nutrients
and to prevent wetting when it’s
raining. Furthermore, Mangifera indica
leaves are found alternating on the plant stalk to exploit the light energy acquired from the sun. This is because of the
fact that Mangifera indica develops best when exposed to sunlight.

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